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Home Products Pre-Made AAV Center AAV-hSyn-ChR2(H134R)-EYFP
Catalog No. AC-09417 · 142 Citations

AAV-hSyn-ChR2(H134R)-EYFP

OptogeneticsNeuron-SpecificIn Stock

A neuron-targeted channelrhodopsin-2 vector for optogenetic excitation. The H134R point mutation increases steady-state photocurrent, and the human synapsin (hSyn) promoter restricts EYFP-tagged expression to neurons. Activate with ~470 nm blue light.

Overview

Pseudorabies virus products

PURIFICATION GRADE
  • Standard
  • Ultra-Purified +$120.00
Price per package $419.00 ≈ $0.40 per 10¹⁰ vg
Ships in 3–4 Weeks
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  • Validated Titer

    Measured by ddPCR

  • Full Plasmid Map

    GenBank + datasheet included

  • QC Guaranteed

    Sterility + endotoxin tested

Catalog number AC-09417
Vector type Recombinant adeno-associated virus (rAAV)
Available serotypes AAV9, AAV5, PHP.eB, AAV2, AAV-retro
Promoter hSyn — human synapsin, neuron-specific
Transgene ChR2(H134R)
Reporter EYFP (enhanced yellow fluorescent protein)
Excitation wavelength ~470 nm (blue)
Titer ≥ 1 × 10¹³ vg/mL (ddPCR verified)
Available volumes 100 µL · 500 µL · 1 mL
Formulation PBS with 0.001% Pluronic F-68
Storage −80 °C
Biosafety level BSL-1

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Terms & License

  • Academic/Nonprofit Terms

    Terms of Use for Viral Vectors

  • Industry Terms

    Not Available to Industry

Citations

  • Nature Neuroscience · 2024
    Synapsin-driven ChR2(H134R) enables reliable cortical interneuron control during behavior
    Reyes M., Okonkwo A., Lindqvist S. et al.
  • Cell Reports · 2023
    Closed-loop optogenetic excitation of hippocampal circuits with AAV9-delivered channelrhodopsin
    Reyes M., Okonkwo A., Lindqvist S. et al.
  • eLife · 2023
    Comparing photocurrent kinetics across channelrhodopsin variants in deep-brain projections
    Costa R., Nakamura H., Bauer J. et al.

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