We are excited to announce the availability of jGCaMP8 calcium sensors packaged in the BBB-crossing PHP.eB capsid. These sensors offer faster kinetics and improved signal-to-noise ratio compared to previous generations, enabling more accurate tracking of neuronal activity. The PHP.eB capsid allows effective transduction throughout the brain after systemic injection, reducing the need for invasive surgeries. This product launch includes detailed characterization data, including fluorescence response times and in vivo imaging results. Researchers can now order pre-made AAVs for immediate use in their calcium imaging experiments.